Hepatitis E is inflammation of the liver caused by the hepatitis E virus (HEV). The virus has at least 4 different types: genotypes 1, 2, 3 and 4. Genotypes 1 and 2 have been found only in humans. Genotypes 3 and 4 circulate in several animals including pigs, wild boars and deer without causing any disease, and occasionally infect humans. The virus is shed in the stools of infected persons and enters the human body through the intestine. It is transmitted mainly through contaminated drinking water. The infection is usually self-limiting and resolves within 2–6 weeks. Occasionally a serious disease known as fulminant hepatitis (acute liver failure) develops, which can be fatal. What Is Hepatitis E? Hepatitis E is a potentially serious acute disease. It is caused by the hepatitis E virus (HEV). The virus targets the liver. According to the World Health Organization (WHO), 20 million cases of hepatitis E infection occur every year, and 44,000 of these cases resulted in death in 2015. It i...